| Product Name | DECR1 Antibody (N-14) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping near the N-terminus of DECR1 of human origin |
| Modification Notes | Beta oxidation refers to the enzymatic process by which Acyl-CoA is catalytically broken down to yield Acetyl-CoA, the first molecule required for the Krebs cycle. DECR1 (2,4-dienoyl-CoA reductase, mitochondrial), also known as DECR, is a 335 amino acid mitochondrial protein that exists as a homotetramer and belongs to the family of short-chain dehydrogenases/reductases. Expressed in heart, pancreas, liver, lung, kidney and skeletal muscle, DECR1 functions as an auxiliary enzyme of beta-oxidation where it participates in the metabolism of unsaturated fatty enoyl-CoA esters. Specifically, DECR1 uses NADP+ to catalyze the reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA, which can then be used as an intermediate in the Krebs cycle. Additionally, DECR1 is thought to function as a tumor suppressor, possibly down regulating the expression of Neu and slowing the rate of tumorigenesis. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of DECR1 of human origin by WB, IF and ELISA non cross-reactive with family member DECR2: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the N-terminus of DECR1 of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the N-terminus of DECR1 of human origin |
| Entrez Gene | 1666 |
|---|
| Application Notes | recommended for detection of DECR1 of human origin by WB, IF and ELISA non cross-reactive with family member DECR2: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
