Application
Western blot analysis of IGF2BP2 expression in Hep G2 whole cell lysate.Application
Western blot analysis of IGF2BP2 expression in non-transfected 293T: (A), human IGF2BP2 transfected 293T: (B) and Hep G2 (C) whole cell lysates.| Product Name | IGF2BP2 Antibody (P-16) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of IGF2BP2 of human origin |
| Modification Notes | IGF2BP2 (insulin-like growth factor 2 mRNA binding protein 2) is also known as IGF2 mRNA-binding protein 2, IMP-2 (IGF-II mRNA-binding protein 2), VICKZ family member 2 or hepatocellular carcinoma autoantigen p62 and is a 556 amino acid protein. IGF2BP2 is expressed in a variety of tissues including heart, placenta, skeletal muscle, pancreas, fetal liver, lung, kidney, thymus and gonadal cells. IGF2BP2 is an RNA binding protein which may be involved in the regulation of mRNA translation and may also function to control the spatial localization of target mRNAs. Antibodies against IGF2BP2 have been detected in patients with HCC (hepatocellular carcinoma), suggesting that IGF2BP2 may have a role in the pathogenesis of HCC. Defects in IGF2BP2 are thought to be associated with susceptibility to type 2 diabetes mellitus. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of IGF2BP2 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with family member IGF2AS also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of IGF2BP2 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of IGF2BP2 of human origin |
| Entrez Gene | 10644 |
|---|
Application
Western blot analysis of IGF2BP2 expression in Hep G2 whole cell lysate.
Application
Western blot analysis of IGF2BP2 expression in non-transfected 293T: (A), human IGF2BP2 transfected 293T: (B) and Hep G2 (C) whole cell lysates.| Application Notes | recommended for detection of IGF2BP2 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with family member IGF2AS also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
