Application
Western blot analysis of connexin 40.1 expression in Hep G2 whole cell lysate.| Product Name | connexin 40.1 Antibody (D-23) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of connexin 40.1 of human origin by WB, IP and ELISA |
| Modification Notes | The connexin family of proteins form hexameric complexes called connexons that facilitate movement of low molecular weight proteins between cells via gap junctions. Connexin proteins share a common topology of four transmembrane alpha-helical domains, two extracellular loops, a cytoplasmic loop and cytoplasmic N- and C-termini. Many of the key functional differences between connexins arise from specific amino-acid substitutions in the most highly conserved domains: the transmembrane and extracellular regions. Connexin 40.1, also known as GJD4 (gap junction protein, delta 4, 40.1kDa) or CX40.1, is a 370 amino acid multi-pass membrane protein that localizes to the cell junction and is expressed in liver, heart, kidney, pancreas, placenta and skeletal muscle. Existing as a component of hexameric connexin complexes, connexin 40.1 helps to facilitate the diffusion of low molecular weight proteins from one cell to another cell. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of connexin 40.1 of human origin by WB IP and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of connexin 40.1 of human origin by WB, IP and ELISA |
| Entrez Gene | 219770 |
|---|
Application
Western blot analysis of connexin 40.1 expression in Hep G2 whole cell lysate.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
