Application
Western blot analysis of MTCH1 expression in Hep G2 whole cell lysate.Application
Western blot analysis of MTCH1 expression in mouse brain tissue extract.| Product Name | MTCH1 Antibody (F-24) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of MTCH1 of mouse, rat and human origin by WB, IP and ELISA |
| Modification Notes | MTCH1 (mitochondrial carrier homolog 1), also known as PSAP or PIG60, is a 389 amino acid multi-pass membrane protein that localizes to the inner mitochondrial membrane and contains two solcar repeats. Expressed in a variety of tissues with highest expression in brain, MTCH1 interacts with Presenilin 1 and is thought to functions as a mitochondrial transporter that may play a role in apoptosis. Multiple isoforms of MTCH1 exist due to alternative splicing events. The gene encoding MTCH1 maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of MTCH1 of mouse rat and human origin by WB IP and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of MTCH1 of mouse, rat and human origin by WB, IP and ELISA |
| Entrez Gene | 23787 |
|---|
Application
Western blot analysis of MTCH1 expression in Hep G2 whole cell lysate.
Application
Western blot analysis of MTCH1 expression in mouse brain tissue extract.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
