Transmembrane emp24 domain-containing protein 3 (TMED3), also known as membrane protein p24B, P24B or C15orf22, is a 217 amino acid member of the EMP24/GP25L family. Localized to the golgi apparatus, TMED3 is a single-pass type I membrane protein containing one GOLD domain. The GOLD (golgi dynamics) domain is a region of about 90 to 150 amino acids that mediates protein-protein interactions. Interacting with lipid, sterol or fatty acid-binding domains, suggesting an association with membrane proteins, the GOLD domain has also been found to interact with the RUN domain, which interacts with cytoskeletal filaments. Two isoforms of TMED3 exist as a result of alternate splicing events.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPELISA
recommended for detection of TMED3 of human origin by WB, IP and ELISA: