Application
Antibodies tested include p-Synapsin Ia/b (Ser 9): (A, B) and Synapsin Ia/b (H-170): (C, D).Application
Antibodies tested include p-Synapsin Ia/b (Ser 9): (A, B, C) and Synapsin Ia/b (H-170): (D, E, F).| Product Name | p-Synapsin Ia/b Antibody (Ser 9) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to phosphorylated Ser 9 of Synapsin Ia/b of human origin |
| Modification | Phosphoralated |
| Modification Notes | Synapsin I, which exists as two alternatively spliced isoforms designated Synapsin Ia and Synapsin Ib, has been characterized as one of the major phosphoproteins in nerve terminals and is thought to be involved in the regulation of neurotransmitter release. Synapsin I cross-links synaptic vesicles and the cytoskeleton, and the interactions of synapsins with actin filaments and synaptic vesicles are regulated by phosphorylation by calmodulin-dependent protein kinase II and cAMP-dependent protein kinase. Posttranslational modifications of Synapsin I result in phosphorylation of the protein at different sites and by different kinases. The Ser 553 residue of Synapsin I is phosphorylated in vivo. This phosphorylation site is immediately followed by a proline, suggesting that Synapsin I is an in vivo substrate of the proline-directed protein kinase, Cdk5. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIP |
| recommended for detection of Ser 9 phosphorylated Synapsin Ia/b of mouse, rat and human origin by WB and IP: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to phosphorylated Ser 9 of Synapsin Ia/b of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to phosphorylated Ser 9 of Synapsin Ia/b of human origin |
| Entrez Gene | 6853 |
|---|
Application
Antibodies tested include p-Synapsin Ia/b (Ser 9): (A, B) and Synapsin Ia/b (H-170): (C, D).
Application
Antibodies tested include p-Synapsin Ia/b (Ser 9): (A, B, C) and Synapsin Ia/b (H-170): (D, E, F).| Application Notes | recommended for detection of Ser 9 phosphorylated Synapsin Ia/b of mouse, rat and human origin by WB and IP: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
