Application
Western blot analysis of ICAP-1 expression in mouse brain tissue extract.| Product Name | ICAP-1 Antibody (FL-200) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-200 representing full length ICAP-1 of human origin |
| Modification Notes | ICAP-1 (Integrin beta-1-binding protein 1, Integrin cytoplasmic domain-associated protein 1) is a 200 amino acid protein encoded by the human gene ITGB1BP1. Integrins are transmembrane heterodimeric receptors for extracellular matrix and cell surface proteins. The binding of integrins to ligands in the extracellular matrix is linked to cell attachment and spreading, which in turn activates various cytosolic signal cascades to promote cell migration, survival, proliferation, and differentiation. ICAP-1 interacts with the cytoplasmic domain of Integrin b1 (ITGB1) to facilitate the recruitment of Integrin b1 to the focal contacts during integrin-dependent cell adhesion. ICAP-1 is a cytoplasmic protein that is primarily expressed in intestine, colon, testis, ovary, thymus, spleen and prostate. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ICAP-1 of mouse and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-200 representing full length ICAP-1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-200 representing full length ICAP-1 of human origin |
| Entrez Gene | 9270 |
|---|
Application
Western blot analysis of ICAP-1 expression in mouse brain tissue extract.| Application Notes | recommended for detection of ICAP-1 of mouse and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
