| Product Name | SLC4A7 Antibody (L-15) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping near the C-terminus of SLC4A7 of human origin |
| Modification Notes | SLC4A7 (solute carrier family 4 member 7), also known as sodium bicarbonate cotransporter 3, is a 1,214 amino acid multi-pass membrane protein that mediates the movement of sodium and bicarbonate across the cell membrane. Studies in mice have shown that hydrogen ion disposal mediated by SLC4A7 is essential for auditory and visual systems, therefore, defects in the gene encoding SLC4A7 may result in the human manifestation of Usher syndrome, a leading cause of deafblindness. With highest expression in spleen and testis, SLC4A7 is also expressed in a variety of other tissues, including brain, skeletal muscle and heart. Due to its critical role in intracellular pH regulation, SLC4A7 is notably affected by hypoxic states during which protein levels are decreased, presumably for reduction of energy consumption. There are five isoforms of SLC4A7 that exist as a result of alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of SLC4A7 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with other SLC family members also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the C-terminus of SLC4A7 of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the C-terminus of SLC4A7 of human origin |
| Entrez Gene | 9497 |
|---|
| Application Notes | recommended for detection of SLC4A7 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with other SLC family members also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
