Application
Western blot analysis of IL-18R expression in non-transfected: (A) and mouse IL-18R transfected: (B) 293T whole cell lysates.| Product Name | IL-18R Antibody (M-307) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Interleukin-18 (IL-18) has been identified as a molecule that induces IFN-g production and enhances NK cell cytotoxicity. IL-18 receptor (IL-18R) is a type I membrane protein present in lung, leukocytes, spleen, liver, thymus, prostate, small intestine, colon, placenta and heart, absent from brain, skeletal muscle, pancreas and kidney. IL-18R is present in Hodgkin’s disease cell lines, and does not bind IL-1å or IL-1∫. The association of IL-18 to IL-18R leads to activation of NF˚B. At present two subunits of IL-18R have been characterized: IL-18Rå and IL-18R∫. IL-18Rå has been described as the ligand-binding chain and IL-18R∫ as the signal-transduction chain. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of IL-18R of mouse and rat origin by WB, IP, IF and ELISA | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 20-326 mapping within an N-terminal extracellular domain of IL-18R of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 20-326 mapping within an N-terminal extracellular domain of IL-18R of mouse origin |
| Entrez Gene | 16182 |
|---|
Application
Western blot analysis of IL-18R expression in non-transfected: (A) and mouse IL-18R transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of IL-18R of mouse and rat origin by WB, IP, IF and ELISA |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
