Application
Western blot analysis of EGFL7 expression in mouse brain tissue extract.Application
Western blot analysis of EGFL7 expression in non-transfected 293: (A), human EGFL7 transfected 293: (B) and ECV304 (C) whole cell lysates.| Product Name | EGFL7 Antibody (H-90) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Epidermal growth factor (EGF) repeat-containing proteins constitute an expanding family of proteins that are involved in several cellular activities, such as blood coagulation, fibrinolysis, cell adhesion, and neural and vertebrate development. A human EGF repeat superfamily member that maps to human chromosome X, EGFL6, encodes a predicted signal peptide suggesting that it is secreted. EGFL6 is expressed in brain and lung tumors and fetal tissues, but is generally absent from normal adult tissues. EGFL7 is a secreted protein that regulates vascular tubulogenesis in vivo. In vitro, EGFL7 inhibits platelet-derived growth factor induced smooth muscle cell migration and promotes adhesion of endothelial cells to the substrate. EGFL7 is expressed specifically by endothelial cells of the heart, lung and kidney. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of EGFL7 of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA also reactive with additional species, including bovine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 184-273 mapping at the C-terminus of EGFL7 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 184-273 mapping at the C-terminus of EGFL7 of human origin |
| Entrez Gene | 51162 |
|---|
Application
Western blot analysis of EGFL7 expression in mouse brain tissue extract.
Application
Western blot analysis of EGFL7 expression in non-transfected 293: (A), human EGFL7 transfected 293: (B) and ECV304 (C) whole cell lysates.| Application Notes | recommended for detection of EGFL7 of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA also reactive with additional species, including bovine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
