| Product Name | Magmas Antibody (H-110) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Magmas, also known as TIMM16, is a 125 amino acid protein that localizes to the inner mitochondrial membrane and belongs to the TIM16/PAM16 family. Expressed ubiquitously, Magmas functions as a probable component of the PAM complex, a multi-protein structure that is required for the ATP-dependent translocation of peptide-containing proteins from the inner membrane membrane into the mitochondrial matrix. Specifically, Magmas may be necessary for the regulation of the ATP-dependent nature of the PAM complex. The gene encoding Magmas maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of Magmas of mouse, rat and human origin by WB, IF and ELISA also reactive with additional species, including canine, bovine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-110 mapping at the N-terminus of Magmas of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-110 mapping at the N-terminus of Magmas of human origin |
| Entrez Gene | 51025 |
|---|
| Application Notes | recommended for detection of Magmas of mouse, rat and human origin by WB, IF and ELISA also reactive with additional species, including canine, bovine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
