Application
Western blot analysis of ZNF395 expression in non-transfected: (A) and human ZNF395 transfected: (B) 293T whole cell lysates.| Product Name | ZNF395 Antibody (L-20) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF395 (Zinc finger protein 395), also known as PBF (Papillomavirus-binding factor) and HDBP2 (Huntington disease gene regulatory region-binding protein 2), is a 513 amino acid protein that contains one C2H2-type zinc finger. ZNF395 binds to the 3’-CCGG-5’ sequence within the papillomavirus promoter adjacent to a RUNX1-binding motif. It has also been established that ZNF395 binds to a seven base pair region within the Huntington's disease (HD) gene promoter, an essential element for HD gene expression. ZNF395 is widely expressed and probably shuttles between the nucleus and cytoplasm. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ZNF395 of human and rat origin by WB, IP, IF and ELISA non cross-reactive with other ZNF family members also reactive with additional species, including equine, canine, bovine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of ZNF395 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of ZNF395 of human origin |
| Entrez Gene | 55893 |
|---|
Application
Western blot analysis of ZNF395 expression in non-transfected: (A) and human ZNF395 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of ZNF395 of human and rat origin by WB, IP, IF and ELISA non cross-reactive with other ZNF family members also reactive with additional species, including equine, canine, bovine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
