Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human pancreas tissue showing nuclear and cytoplasmic staining of glandular cells.Application
Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear localization.| Product Name | Neurogenin 2 Antibody (H-55) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | The neurogenin family of proteins belongs to the basic helix-loop-helix (bHLH) superfamily and consists of neurogenin 1, neurogenin 2 and neurogenin 3 (also designated ngn3). bHLH members are transcriptional regulators that determine cell fate. During mouse neurogenesis, Neurogenin 1 and Neurogenin 2 are expressed in distinct progenitor populations in the central and peripheral nervous systems. Targeted mutation analyses showed that Neurogenin 1 is essential for the determination of neuronal precursors for proximal cranial sensory ganglia and that Neurogenin 2 is essential for the determination of precursors for epibranchial placode-derived sensory neurons. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of Neurogenin 2 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA also reactive with additional species, including canine and bovine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 68-122 mapping within an internal region of Neurogenin 2 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 68-122 mapping within an internal region of Neurogenin 2 of human origin |
| Entrez Gene | 63973 |
|---|
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human pancreas tissue showing nuclear and cytoplasmic staining of glandular cells.
Application
Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear localization.| Application Notes | recommended for detection of Neurogenin 2 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA also reactive with additional species, including canine and bovine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
