Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human liver tissue showing membrane and cytoplasmic staining of hepatocytes.Application
Western blot analysis of OATP8 expression in HeLa whole cell lysate.| Product Name | OATP8 Antibody (H-52) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | The organic anion transporter family of proteins mediate hepatic uptake of cardiac glycosides. OATP8 (organic anion transporter 8), also known as SLCO1B3 (solute carrier organic anion transporter family member 1B3), SLC21A8 (solute carrier family 21 member 8) or LST-2 (liver-specific organic anion transporter 2), is a 702 amino acid member of the organic anion transporter protein family. As a multi-pass membrane protein, OATP8 mediates the Na+-independent transport of triiodothyronine (T3), leukotriene C4, taurochlate and other organic anions. OATP8 is also thought to transport steroid conjugates, such as 17-beta-glucuronosyl estradiol and dehydroepiandrosterone sulfate (DHEAS). Oatp4 is highly expressed in liver and is N-glycosylated. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of OATP8 and, to a lesser extent OATP-C of human origin by WB, IP, IF, IHC(P) and ELISA | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 651-702 mapping at the C-terminus of OATP8 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 651-702 mapping at the C-terminus of OATP8 of human origin |
| Entrez Gene | 28234 |
|---|
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human liver tissue showing membrane and cytoplasmic staining of hepatocytes.
Application
Western blot analysis of OATP8 expression in HeLa whole cell lysate.| Application Notes | recommended for detection of OATP8 and, to a lesser extent OATP-C of human origin by WB, IP, IF, IHC(P) and ELISA |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
