| Product Name | group X sPLA2 Antibody (H-75) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Phospholipases catalyze the release of fatty acids from phospho-lipids (1). One member of the phospholipase family, iPLA2, is detected as a membrane-bound protein with multiple smaller isoforms, which result from alternative splicing (2). Another phopholipase, sPLA2, belongs to a family of secretory phospholipases A2, which represent an expanding family of related enzymes (3,4). sPLA2 has both membrane bound and secreted forms that are encoded by a single gene which maps to human chromosome 1p35 (5,6). sPLA2 is involved in the regulation of phospholipid metabolism in biomembranes and in eicosanoid biosynthesis (5). Group X sPLA2 mRNA is found in various tissues including the lung, thymus, and spleen, and immunohistochemical analysis reveals its expression in splenic macrophages (3). Group X sPLA2 is an actively secreted enzyme that maps to human chromosome 16p13.1-p12 (4). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of group X secretory PLA2 of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 81-155 mapping at the C-terminus of group X sPLA2 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 81-155 mapping at the C-terminus of group X sPLA2 of human origin |
| Entrez Gene | 8399 |
|---|
| Application Notes | recommended for detection of group X secretory PLA2 of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
