Application
Western blot analysis of human TAF II p70 transfected 293T whole cell lysate.Application
Immunoperoxidase staining of formalin-fixed, paraffin-embedded human kidney tissue showing cytoplasmic localization.| Product Name | TAF II p70 Antibody (S-22) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | TFIID is a general transcription factor that facilitates the preinitiation complex assembly through direct interactions with the TATA promoter element. TFIID is a multisubunit complex consisting of a small TATA-binding polypeptide and other TBP-associated factors (TAFs). The TAF II family members include p18, p20, p28, p30, p31, p32, p70, p100, p105, p130, p170 and p250, which is the largest subunit of TFIID. TAF II p70 (TATA-binding protein (TBP) associated factor II70), also known as TAF6, TAF2E, TAFII70, TAFII80 or TAFII85, is a member of the basal transcription complex. TAF II p70 directly interacts with TAF II p31, TAF II p20 and TAF II p250. It forms a heterodimer with TAF II p31 and may function as a p53 coactivator. The TAF II p70/TAF II p31 heterodimer forms a histone-like octamer complex with the TAF II p105/TAF II p20 heterodimer. Several TAF II p70 isoforms exist due to alternative splicing. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of TAF II p70 of mouse rat and human origin by WB IP IF IHC(P) and ELISA also reactive with additional species including canine |
|---|---|
| Tissue Specificity | recommended for detection of TAF II p70 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including canine |
| Entrez Gene | 6878 |
|---|
Application
Western blot analysis of human TAF II p70 transfected 293T whole cell lysate.
Application
Immunoperoxidase staining of formalin-fixed, paraffin-embedded human kidney tissue showing cytoplasmic localization.| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
