Application
Western blot analysis of NHEDC1 expression in human fetal brain tissue extract.| Product Name | NHEDC1 Antibody (K-24) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | The Na+/H+ exchangers (NHEs) catalyze the transport of Na+ in exchange for H+ across membranes in organisms and are required for numerous physiological processes. NHEDC1 (Na+/H+ exchanger domain containing 1), also known as sodium/hydrogen exchanger-like domain-containing protein 1 or NHE domain-containing protein 1, is a 515 amino acid multi-pass membrane protein belonging to the monovalent cation:proton antiporter 1 (CPA1) transporter family. Only expressed in testis, NHEDC1 is highly conserved in mammals including human, mouse, rat and Macaca fascicularis. The gene encoding NHEDC1 maps to human chromosome 4, which houses nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of NHEDC1 of human origin by WB IP and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of NHEDC1 of human origin by WB, IP and ELISA |
| Entrez Gene | 150159 |
|---|
Application
Western blot analysis of NHEDC1 expression in human fetal brain tissue extract.| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
