| Product Name | α/β-centractin Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 77-376 mapping at the C-terminus of α-centractin of human origin |
| Modification Notes | The dynactin complex is a macromolecular complex that consists of 10-11 distinct subunits. This complex is critical for the function of dynein, a molecular motor protein. Dynactin plays a role in ER to Golgi transport, spindle formation, chromosome movement, axon guidance, nuclear positioning and the centripetal movement of lysosomes and endosomes. Centractin is a subunit of the dynactin complex that exists in multiple isoforms. The å isoform, also known as actin-related protein 1 homolog A (Arp1) and previously referred to as centractin, is the most abundant isoform in the dynactin complex. The ∫ isoform, also known as actin-related protein 1 homolog B, shares 90% identity with the å isoform. The two isoforms, å and ∫, are expressed at a ratio of 15:1 respectively. The backbone filament structure of the dynactin complex (important for the arrangement of other complex proteins) is composed of 9-11 subunits of å/∫-centractin. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of α-centractin and β-centractin of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 77-376 mapping at the C-terminus of &alpha -centractin of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 77-376 mapping at the C-terminus of α-centractin of human origin |
| Entrez Gene | 10121 |
|---|
| Application Notes | recommended for detection of α-centractin and β-centractin of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
