Application
Western blot analysis of α-internexin expression in IMR-32 whole cell lysate.Application
Western blot analysis of α-internexin expression in HeLa whole cell lysate.| Product Name | α-internexin Antibody (H-90) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Alpha-internexin is a brain specific type IV intermediate filament protein. This axonal protein is found in most, if not all, neurons of the CNS. The head domain of alpha-internexin is essential for self-assembly into a filament network. Expression levels of alpha-internexin have been shown to be maximal during late embryogenesis and to decline into adulthood, suggesting that this protein plays a role in regulatory processes during the development of the brain. The alpha-internexin promoter has been shown to be activated by Brn-3a or Brn-3c transcription factor binding, while Brn-3b binding to the promoter results in alpha-internexin repression. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of &alpha-internexin of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine and bovine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 410-499 mapping at the C-terminus of &alpha -internexin of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 410-499 mapping at the C-terminus of α-internexin of human origin |
| Entrez Gene | 9118 |
|---|
Application
Western blot analysis of α-internexin expression in IMR-32 whole cell lysate.
Application
Western blot analysis of α-internexin expression in HeLa whole cell lysate.| Application Notes | recommended for detection of &alpha-internexin of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine and bovine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
