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NFATc4 Antibody (L-9)

Catalog Number:OM188845
OM188845
Discount Price
OM188845-100ul
1~2 Week
100ul
OM188845-50ul
50ul
OM188845-20ul
20ul
1~2 Week
Product Profile
Product Name NFATc4 Antibody (L-9)
Antibody Type Primary Antibodies
Modification Notes NFATc4 (nuclear factor of activated T cells, cytoplasmic, calcineurin-dependent 4) is a member of the nuclear factors of activated T cells DNA-binding transcription complex that influences cytokine gene expression, cardiac hypertrophy and adipocyte differentiation. This complex consists of at least two components: a cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate in the formation of this complex. NFATc4 plays a role in the inducible expression of cytokine genes in T cells, including the induction of IL-2 and IL-4. p38 MAP kinase phosphorylates multiple residues in the NFAT homology domain of NFATc4.
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIPIFIHCELISA
recommended for detection of NFATc4 SP-2 domain of mouse and human origin by WB, IP, IF, IHC(P) and ELISA
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Alternative Names epitope mapping near the N-terminus of NFATc4 of human origin
Tissue Specificity epitope mapping near the N-terminus of NFATc4 of human origin
Database Links
Entrez Gene 4776
Application

Application

Immunoperoxidase staining of formalin fixed, paraffin-embedded human broncus tissue showing nuclear and cytoplasmic staining of respiratory epithelial cells at low magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

Application

Immunoperoxidase staining of formalin fixed, paraffin-embedded human broncus tissue showing nuclear and cytoplasmic staining of respiratory epithelial cells at high magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

Application

Western blot analysis of NFATc4 expression in non-transfected: (A) and mouse NFATc4 transfected: (B) 293T whole cell lysates.

Application

Western blot analysis of NFATc4 expression in non-transfected: (A) and human NFATc4 transfected: (B) 293T whole cell lysates.
Application Notes recommended for detection of NFATc4 SP-2 domain of mouse and human origin by WB, IP, IF, IHC(P) and ELISA
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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