| Product Name | NTF2 Antibody (FL-127) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Protein transport across the nucleus is a selective, multistep process involving several cytoplasmic factors (1,2). Proteins must be recognized as import substrates, dock at the nuclear pore complex and translocate across the nuclear envelope in an ATP-dependent fashion (2). Two cytosolic factors centrally involved in the recognition and docking process are karyopherin-å and karyopherin-∫proteins. The karyopherin holoenzyme is a heterodimer of å and ∫ subunits (3,4). Karyopherin-å functions in the recognition and targeting of substrates destined for nuclear import, while karyopherin-∫ serves as an adapter, tethering the karyopherin-å/substrate complex to docking proteins on the nuclear envelope termed nucleoporins (5). p62 glycoprotein is one such nucleoporin, and is not only involved in the nuclear import of proteins, but also the export of nascent mRNA strands (6,7). An additional protein, NTF2 (nuclear transport factor 2), interacts with nucleoporin p62 as a homodimer and may be an obligate component of functional p62 (8). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of NTF2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-127 raised against full length NTF2 of human origin NTF2 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-127 raised against full length NTF2 of human origin NTF2 of human origin |
| Entrez Gene | 10204 |
|---|
| Application Notes | recommended for detection of NTF2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
