Application
Western blot analysis of AHSP expression in human PBL whole cell lysate.| Product Name | AHSP Antibody (FL-102) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-102 representing full length AHSP of human origin |
| Modification Notes | å-hemoglobin stabilizing protein (AHSP), also designated erythroid associated factor (ERAF), is an erythroid-specific protein that acts as a chaperone to prevent the aggregation of å-hemoglobin during normal erythroid cell development. It specifically protects free å-hemoglobin from precipitation in live cells and in solution. It forms a heterodimer with free å-hemoglobin, but not with ∫-hemoglobin or hemoglobin A (å2-∫-2). AHSP localizes to the cytoplasm and is expressed in the blood and bone marrow. The AHSP protein is downregulated in transmissible spongiform encephalopathies (TSEs). AHSP may regulate pathological states of å-hemoglobin excess such as ∫-thalassemia, a group of hereditary disorders involving the decreased production of normal adult hemoglobin (HbA) that are characterized by a deficiency in the synthesis of ∫-globin chains. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of AHSP of human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-102 representing full length AHSP of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-102 representing full length AHSP of human origin |
| Entrez Gene | 51327 |
|---|
Application
Western blot analysis of AHSP expression in human PBL whole cell lysate.| Application Notes | recommended for detection of AHSP of human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
