| Modification Notes |
TTP-åL (tocopherol (alpha) transfer protein-like) is a 342 amino acid protein that is thought to bind hydrophobic ligands. Containing one CRAL-TRIO domain, TTP-åL is encoded by a gene that maps to human chromosome 20q13.12. Comprising approximately 2% of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought to be important for seminal production and may be potential targets for male contraception. |