Application
Immunofluorescence staining of methanol-fixed HeLa cells showing perinuclear and membrane localization.Application
Western blot analysis of Gβ 2 expression in non-transfected 293T: (A), mouse Gβ 2 transfected 293T: (B) and Jurkat (C) whole cell lysates.Application
Western blot analysis of Gβ 2 expression in non-transfected: (A) and mouse Gβ 2 transfected: (B) 293T whole cell lysates.Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human salivary gland tissue showing cytoplasmic staining of glandular cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.Application
Western blot analysis of Gβ 2 expression in rat brain extract.| Product Name | Gβ 2 Antibody (C-16) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. Each of a very broad range of receptors specifically detects an extracellular stimulus (i.e. a photon, pheromone, odorant, hormone or neurotransmitter), while the effectors (e.g. adenyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein å, ∫ and © polypeptides are encoded by at least 16, 4 and 7 genes, respectively. Most interest in G proteins has been focused on their å subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Evidence, however, has established an important regulatory role for the ∫© subunits. The G protein ∫ subunits are important regulators of G protein å subunits as well as of certain signal transduction receptors and effectors. In mammals, there are five different members of the ∫ subunit family |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of G&beta 2 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA also reactive with additional species, including equine, canine, bovine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within a divergent domain in the N-terminus of G&beta 2 of mouse origin |
|---|---|
| Tissue Specificity | epitope mapping within a divergent domain in the N-terminus of Gβ 2 of mouse origin |
| Entrez Gene | 2783 |
|---|
Application
Immunofluorescence staining of methanol-fixed HeLa cells showing perinuclear and membrane localization.
Application
Western blot analysis of Gβ 2 expression in non-transfected 293T: (A), mouse Gβ 2 transfected 293T: (B) and Jurkat (C) whole cell lysates.
Application
Western blot analysis of Gβ 2 expression in non-transfected: (A) and mouse Gβ 2 transfected: (B) 293T whole cell lysates.
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human salivary gland tissue showing cytoplasmic staining of glandular cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
Application
Western blot analysis of Gβ 2 expression in rat brain extract.| Application Notes | recommended for detection of G&beta 2 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA also reactive with additional species, including equine, canine, bovine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
