epitope mapping within a C-terminal cytoplasmic domain of SCAMP4 of human origin
Modification Notes
Secretory carrier membrane proteins (SCAMPs) are components of post Golgi membranes that are invovled in endocytosis, vesicle recycling and membrane trafficking. The structural features of SCAMPs include multiple N-terminal NPF repeats and four highly conserved transmembrane regions. These NPF repeats frequently interact with EH domain proteins and aid in the budding of transport vesicles from the plasma membrane or the Golgi complex. Endocytic budding at the plasma membrane and vesicle budding at the trans-Golgi complex facilitates binding of SCAMP proteins to EH domain proteins. SCAMPs exist as distinct but related proteins that include SCAMP1, SCAMP2, SCAMP3 and SCAMP4. SCAMP4 (secretory carrier membrane protein 4) is a 229 amino acid multi-pass membrane protein that exists as three alternatively spliced isoforms and is encoded by a gene located on human chromosome 19p13.3.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of SCAMP4 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other SCAMP family members also reactive with additional species, including equine, canine, bovine and avian:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within a C-terminal cytoplasmic domain of SCAMP4 of human origin
Tissue Specificity
epitope mapping within a C-terminal cytoplasmic domain of SCAMP4 of human origin
Western blot analysis of SCAMP4 expression in non-transfected: (A) and human SCAMP4 transfected: (B) 293T whole cell lysates.
Application Notes
recommended for detection of SCAMP4 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other SCAMP family members also reactive with additional species, including equine, canine, bovine and avian:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.