| Product Name | SPOPL Antibody (N-16) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping at the N-terminus of SPOPL of human origin |
| Modification Notes | SPOPL (speckle-type POZ protein-like), also known as HIB homolog 2 or Roadkill homolog 2, is a 392 amino acid nuclear protein that may be involved in ubiquitination and proteasomal degradation processes. Belonging to the Tdpoz family, SPOPL contains one BTB (POZ) domain and one MATH domain. SPOPL forms a complex with a member of the cullin family. The gene that encodes SPOPL includes 71,768 bases, four transcripts and maps to the human chromosome 2q22.1. Chromosomal arm 2q22-23 has been identified as one of fifteen hot spots thought to be involved in head and neck squamous cell carcinoma (HNSCC). Chromosome 2, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alström syndrome. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of SPOPL of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with SPOP also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping at the N-terminus of SPOPL of human origin |
|---|---|
| Tissue Specificity | epitope mapping at the N-terminus of SPOPL of human origin |
| Entrez Gene | 339745 |
|---|
| Application Notes | recommended for detection of SPOPL of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with SPOP also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
