epitope mapping near the C-terminus of GLB1L2 of human origin
Modification Notes
GLB1L2 (beta-galactosidase-1-like protein 2) is a 636 amino acid secreted protein belonging to the glycosyl hydrolase 35 family. The gene encoding GLB1L2 maps to human chromosome 11q25. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of GLB1L2 of human origin by WB, IP, IF and ELISA non cross-reactive with GLB1L or GLB1L3 also reactive with additional species, including canine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping near the C-terminus of GLB1L2 of human origin
Tissue Specificity
epitope mapping near the C-terminus of GLB1L2 of human origin
Western blot analysis of GLB1L2 expression in DU 145 (A), PC-3 (B) and A549 (C) whole cell lysates and human kidney tissue extract (D).
Application Notes
recommended for detection of GLB1L2 of human origin by WB, IP, IF and ELISA non cross-reactive with GLB1L or GLB1L3 also reactive with additional species, including canine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.