Application
Western blot analysis of ANKMY2 expression in non-transfected: (A) and human ANKMY2 transfected: (B) 293T whole cell lysates.| Product Name | ANKMY2 Antibody (T-12) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping near the N-terminus of ANKMY2 of human origin |
| Modification Notes | ANKMY2 (ankyrin repeat and MYND domain containing 2) is a 441 amino acid protein that contains three ANK repeats and one MYND-type zinc finger. Encoded by a gene that maps to human chromosome 7p21.1, ANKMY2 is conserved in chimpanzee, dog, cow, mouse, chicken, zebrafish, fruit fly, mosquito and Caenorhabditis elegans. Downregulation of ANKMY2, associated with frequent deletions of human chromosome 7p22.1, indicate that ANKMY2 may role a role in the pathogenesis of natural killer (NK)-cell malignancies. ANKMY2 is also upregulated by enforced expression of Hox11, which functions broadly to hinder hemopoiesis, diverts differentiation to an alternative fate and promotes pre-leukaemic states. ANKMY2 may also participate in zinc ion binding, cell adhesion, cellular morphogenesis, neurite outgrowth and human cortical functions. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ANKMY2 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with ANKMY1 also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the N-terminus of ANKMY2 of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the N-terminus of ANKMY2 of human origin |
| Entrez Gene | 57037 |
|---|
Application
Western blot analysis of ANKMY2 expression in non-transfected: (A) and human ANKMY2 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of ANKMY2 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with ANKMY1 also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
