| Product Name | NADSYN1 Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-300 mapping at the N-terminus of NADSYN1 of human origin |
| Modification Notes | NAD (nicotinamide adenine dinucleotide) is a cofactor that participates in a wide variety of functions, including metabolic redox reactions, cell signaling events and post-translational protein modifications. The synthesis of NAD within the cell is dependent upon a number of enzymes, called NAD synthetases, that work in concert to catalyze the reactions that form NAD. NADSYN1 (NAD synthetase 1) is a 706 amino acid protein that contains one CN (carbon-nitrogen) hydrolase domain and is a member of the NAD synthetase family. Expressed at high levels in testis, kidney, liver and small intestine, NADSYN1 catalyzes the ATP-dependent conversion of deamido-NAD+ to free NAD+. NADSYN1 exists as a homohexamer that uses both ammonia and glutamate as amide donors. NADSYN1 is present in human promyelocytic leukemia and glioma cell lines, suggesting a possible role in tumor formation. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of NADSYN1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine and bovine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-300 mapping at the N-terminus of NADSYN1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-300 mapping at the N-terminus of NADSYN1 of human origin |
| Entrez Gene | 55191 |
|---|
| Application Notes | recommended for detection of NADSYN1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine and bovine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
