Application
Western blot analysis of FAM13C1 expression in mouse embryo (A) and mouse liver (B) tissue extracts.Application
Western blot analysis of FAM13C1 expression in non-transfected: (A) and human FAM13C1 transfected: (B) 293T whole cell lysates.| Product Name | FAM13C1 Antibody (H-261) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-261 mapping at the N-terminus of FAM13C1 of human origin |
| Modification Notes | FAM13C1 (family with sequence similarity 13, member C), also known as FAM13C, is a 585 amino acid protein that belongs to the FAM13 family. Existing as three alternatively spliced isoforms, the gene encoding FAM13C1 maps to human chromosome 10, which contains over 800 genes, 135 million nucleotides and makes up nearly 4.5% of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. The chromosome 10 encoded gene ERCC6 is important for DNA repair and is linked to Cockayne syndrome which is characterized by extreme photosensitivity and premature aging. Tetrahydrobiopterin deficiency and a number of syndromes involving defective skull and facial bone fusion are also linked to chromosome 10. As with most trisomies, trisomy 10 is rare and is deleterious. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of FAM13C1 of human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-261 mapping at the N-terminus of FAM13C1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-261 mapping at the N-terminus of FAM13C1 of human origin |
Application
Western blot analysis of FAM13C1 expression in mouse embryo (A) and mouse liver (B) tissue extracts.
Application
Western blot analysis of FAM13C1 expression in non-transfected: (A) and human FAM13C1 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of FAM13C1 of human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
