Application
Western blot analysis of ARRDC1 expression in non-transfected 293T: (A), human ARRDC1 transfected 293T: (B) and PC-3 (C) whole cell lysates.| Product Name | ARRDC1 Antibody (S-13) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of ARRDC1 of human origin |
| Modification Notes | ARRDC1, ARRDC2 (which exists as multiple alternatively spliced isoforms), ARRDC4 and ARRDC5 are arrestin domain-containing proteins that are encoded by genes which map to human chromosomes 9, 15 and 19. Chromosome 9, on which the ARRDC1 gene is localized, contains 145 million base pairs and comprises 4% of the human genome, encoding nearly 900 genes. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster. The ARRDC2 and ARRDC5 genes map to chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. Unlike other ARRDC genes, the ARRDC4 gene maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ARRDC1 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other ARRDC family members also reactive with additional species, including equine, canine and bovine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of ARRDC1 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of ARRDC1 of human origin |
| Entrez Gene | 92714 |
|---|
Application
Western blot analysis of ARRDC1 expression in non-transfected 293T: (A), human ARRDC1 transfected 293T: (B) and PC-3 (C) whole cell lysates.| Application Notes | recommended for detection of ARRDC1 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other ARRDC family members also reactive with additional species, including equine, canine and bovine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
