| Product Name | GTPBP1 Antibody (G-19) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of GTPBP1 of human origin |
| Modification Notes | The gene encoding GTPBP1 (GTP-binding protein 1), a 669 amino acid cytoplasmic protein, is highly conserved among species with 97% sequence similarity between the human and mouse homologs. While mainly expressed in smooth muscle, brain, thymus, kidney and lung, expression of GTPBP1 in monocytes can be induced by IFN-©, a finding which is similar with other members of the G protein superfamily. The primary structure of GTPBP1 seems to indicate that it is related to EF-1 å and EF-Tu, G proteins that are important components of protein synthesis machinery. Since mutation of the gene encoding GTPBP1 does not lead to any phenotypic abnormalities, it is thought that there may be a genetic redundancy to make up for GTPBP1 lack-of-function. GTPBP2 shares 44% sequence similarity with GTPBP1 and also overlaps in expression pattern, suggesting that the GTPBP2 gene may compensate for GTPBP1 genetic abnormalities. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of GTPBP1 of mouse, rat and human origin by WB, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of GTPBP1 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of GTPBP1 of human origin |
| Entrez Gene | 9567 |
|---|
| Application Notes | recommended for detection of GTPBP1 of mouse, rat and human origin by WB, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
