Application
Western blot analysis of Complexin-3 expression in mouse prostate (A) and mouse brain (B) tissue extracts.Application
Western blot analysis of Complexin-3 expression in mouse prostate (A), mouse spleen (B) and mouse brain (C) tissue extracts.| Product Name | Complexin-3 Antibody (H-44) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-44 mapping at the N-terminus of Complexin-3 of human origin |
| Modification Notes | Members of the Complexin protein family promote SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) precomplex formation by binding to Syntaxin via an å-helical domain. Complexins are important regulators of transmitter release at a late step in calcium-dependent neurotransmitter release or immediately after the calcium-triggering step of fast synchronous transmitter release. Neurons lacking Complexins show reduced transmitter release efficiency due to decreased calcium sensitivity of the synaptic secretion process. Complexin-3, also known as CPXIII, CPX-III, Nbla11589 or CPLX3, is a 158 amino acid member of the complexin/synaphin family. Complexin-3 is involved in the regulation of synaptic vesicle exocytosis. Complexin-3 binds to the SNARE core complex containing SNAP 25, VAMP-2 and Syntaxin 1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Complexin-3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-44 mapping at the N-terminus of Complexin-3 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-44 mapping at the N-terminus of Complexin-3 of human origin |
Application
Western blot analysis of Complexin-3 expression in mouse prostate (A) and mouse brain (B) tissue extracts.
Application
Western blot analysis of Complexin-3 expression in mouse prostate (A), mouse spleen (B) and mouse brain (C) tissue extracts.| Application Notes | recommended for detection of Complexin-3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
