| Product Name | WDR21A Antibody (G-12) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of WDR21A of human origin |
| Modification Notes | WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking. WDR21A (WD repeat-containing protein 21A), also known as DCAF4 (DDB1 and CUL-4 associated factor 4) or WDR21, is a 495 amino acid protein that contains two WD repeats and may function as a substrate receptor for the CUL-4-DDB1 E3 ubiquitin-protein ligase complex. WRD21A is suggested to participate in protein modification and ubiquitination. WDR21A exists as two alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 14q24.2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of WDR21A isoforms 1 and 2 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with WDR21B or WDR21C also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of WDR21A of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of WDR21A of human origin |
| Entrez Gene | 26094 |
|---|
| Application Notes | recommended for detection of WDR21A isoforms 1 and 2 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with WDR21B or WDR21C also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
