Application
Western blot analysis of SCML2 expression in rat testis (A) and rat lung (B) tissue extracts.| Product Name | SCML2 Antibody (M-265) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 561-825 mapping at the C-terminus of SCML2 of mouse origin |
| Modification Notes | In Drosophila, the Polycomb (PcG) gene family encodes chromatin proteins that are required for the repression of homeotic loci in embryonic development. PcG proteins work in conjunction with the trithorax-group (trxG), which activate homeobox gene expression during embryonic development. SCM (sex comb on midleg) is an important Drosophila PcG protein involved in transcriptional repression. SCML2 (sex comb on midleg-like 2) is a human homolog of this Drosophila protein. SCML2 is a ubiquitously expressed protein with predominant expression in placenta, testis and thymus. Upon DNA damage, SCML2 may be phosphorylated by ATR or ATM. Due to alternative splicing, two isoforms exist for this protein. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of SCML2 of mouse and rat origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 561-825 mapping at the C-terminus of SCML2 of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 561-825 mapping at the C-terminus of SCML2 of mouse origin |
| Entrez Gene | 107815 |
|---|
Application
Western blot analysis of SCML2 expression in rat testis (A) and rat lung (B) tissue extracts.| Application Notes | recommended for detection of SCML2 of mouse and rat origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
