Application
Western blot analysis of ZCCHC6 expression in human prostate tissue extract.| Product Name | ZCCHC6 Antibody (L-13) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of ZCCHC6 of human origin |
| Modification Notes | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZCCHC6 (zinc finger, CCHC domain containing 6), also known as TUTase 7 (terminal uridylyltransferase 7), PAPD6 (PAP associated domain containing 6) or HS2, is a 1,495 amino acid uridylyltransferase that mediates RNA uridylation. A member of the DNA polymerase type-B-like family, ZCCHC6 contains three CCHC-type zinc fingers and two PAP-associated domains, and exists as six alternatively spliced isoforms. The gene encoding ZCCHC6 maps to human chromosome 9q21.33 and mouse chromosome 13 B2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ZCCHC6 isoforms 1-6 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other ZCCHC family members also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of ZCCHC6 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of ZCCHC6 of human origin |
| Entrez Gene | 79670 |
|---|
Application
Western blot analysis of ZCCHC6 expression in human prostate tissue extract.| Application Notes | recommended for detection of ZCCHC6 isoforms 1-6 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other ZCCHC family members also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
