Application
Western blot analysis of CLYBL expression in non-transfected 293T: (A), human CLYBL transfected 293T: (B) and LADMAC (C) whole cell lysates and mouse liver tissue extract (D).Application
Western blot analysis of CLYBL expression in HeLa whole cell lysate.| Product Name | CLYBL Antibody (C-20) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping at the C-terminus of CLYBL of human origin |
| Modification Notes | The citrate lyase subunit beta-like protein (CLYBL) is a 340 amino acid protein that localizes to the mitochondrion where it binds 1 magnesium ion per subunit. The gene encoding human CLYBL maps to chromosome 13, which contains around 114 million base pairs and 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. RB1 encodes a crucial tumor suppressor protein which, when defective, leads to malignant growth in the retina and has been implicated in a variety of other cancers. The gene SLITRK1, which is associated with Tourette syndrome, is on chromosome 13. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. Trisomy 13, also known as Patau syndrome, is quite deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of CLYBL of h and r origin by WB, IP, IF and ELISA also reactive with additional species, including canine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping at the C-terminus of CLYBL of human origin |
|---|---|
| Tissue Specificity | epitope mapping at the C-terminus of CLYBL of human origin |
| Entrez Gene | 171425 |
|---|
Application
Western blot analysis of CLYBL expression in non-transfected 293T: (A), human CLYBL transfected 293T: (B) and LADMAC (C) whole cell lysates and mouse liver tissue extract (D).
Application
Western blot analysis of CLYBL expression in HeLa whole cell lysate.| Application Notes | recommended for detection of CLYBL of h and r origin by WB, IP, IF and ELISA also reactive with additional species, including canine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
