| Modification Notes |
ANT4 (adenine nucleotide translocator 4), also known as ALC25A31 (solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31), AAC4 or SFEC, is a 315 amino acid multi-pass membrane protein that localizes to the inner mitochondrial membrane and contains three solcar repeats. Expressed in testis, brain, sperm and liver, ANT4 functions to catalyze the exchange of ATP and ADP across the mitochondrion, possibly mediating energy generation, energy consumption and, ultimately, motility, in the distal flagellum. The gene encoding ANT4 maps to human chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. |