epitope corresponding to amino acids 18-56 mapping near the N-terminus of Myelin P2 of human origin
Modification Notes
Peripheral Myelin protein-2 (PMP2, Myelin P2, MP2), a small basic enzyme, is one of the principal proteins of peripheral Myelin and presumably participates in the transport of fatty acids or the metabolism of Myelin lipids. Myelin P2 is similar in amino acid sequence and tertiary structure to fatty acid binding proteins found in the liver, adipocytes and intestine, although its expres-sion is restricted to the nervous system. Research indicates that Myelin P2 may play an important role in the organization of compact Myelin; the protein is detected only in Myelin-producing cells of the central and peripheral nervous systems. The 5-prime flanking region of the Myelin P2 gene contains a TA-rich element (TATA-like box) and a single, distinct transcription initiation site. The gene maps to 8q21.3-q22.1 and encodes a cytosolic protein.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of Myelin P2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 18-56 mapping near the N-terminus of Myelin P2 of human origin
Tissue Specificity
epitope corresponding to amino acids 18-56 mapping near the N-terminus of Myelin P2 of human origin
Western blot analysis of Myelin P2 expression in mouse embryonic brain tissue extract.
Application Notes
recommended for detection of Myelin P2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.