| Product Name | FLVCR Antibody (M-115) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-115 mapping at the N-terminus of FLVCR of mouse origin |
| Modification Notes | FLVCR is a 555 amino acid protein encoded by the human gene FLVCR. It is a multi-pass membrane bound protein that belongs to the major facilitator superfamily, Feline leukemia virus subgroup C receptor (TC 2.A.1.28.1) family. FLVCR is responsible for the exportation of cytoplasmic heme groups. It is believed that it may protect developing erythroid cells from heme toxicity. Expression of FLVCR in cells will cause susceptibility to FeLV-C (Feline leukemia virus subgroup C) in vitro. FLVCR is found in all hematopoietic tissues, including peripheral blood lymphocytes and fetal liver, and some expression is found in pancreas and kidney. It is down-regulated in haemopoietic progenitor cells undergoing differentiation and hemoglobinization. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of FLVCR of mouse and rat origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-115 mapping at the N-terminus of FLVCR of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-115 mapping at the N-terminus of FLVCR of mouse origin |
| Entrez Gene | 226844 |
|---|
| Application Notes | recommended for detection of FLVCR of mouse and rat origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
