epitope corresponding to amino acids 18-57 mapping at the C-terminus of Histatin of human origin
Modification Notes
Histatin 1 is a histidine-rich phosphoprotein present in human parotid saliva that possesses candidacidal activity and functions in mineralization by adsorbing to hydroxyapatite. Phosphorylation of histatin 1 contributes to its ability to bind hydroxyapatite. Salivary histatins are a family of small histidine-rich peptides with potent antifungal activity. Submandibular and sublingual histatin secretion levels may affect the status of yeast present in the mouth. As a result, histatins have been implicated as potential therapeutic agents against oral candidiasis. A decrease in salivary histatins in relation to total salivary protein is common in old age and can influence the ability of the oral host defense system to address pathogens.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of Histatin 1 and 2, and to a lesser extent, Histatin 3 of human origin by WB, IP, IF and ELISA:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 18-57 mapping at the C-terminus of Histatin of human origin
Tissue Specificity
epitope corresponding to amino acids 18-57 mapping at the C-terminus of Histatin of human origin
Application Notes
recommended for detection of Histatin 1 and 2, and to a lesser extent, Histatin 3 of human origin by WB, IP, IF and ELISA:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.