Application
Western blot analysis of REEP5 expression in non-transfected: (A) and human REEP5 transfected: (B) 293T whole cell lysates.Application
Western blot analysis of REEP5 expression in HeLa (A), HL-60 (B), Jurkat (C), K-562 (D), MCF7 (E) and HISM (F) whole cell lysates.| Product Name | REEP5 Antibody (E-13) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of REEP5 of human origin |
| Modification Notes | REEP5 (Receptor expression-enhancing protein 5), also known as C5orf18, DP1, TB2 or D5S346, is a 189 amino acid multi-pass membrane protein. Thought to promote the functional cell surface expression of olfactory receptors, REEP5 belongs to the DP1 family and is encoded by a gene that maps to chromosome 5. With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6% of human genomic DNA. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of REEP5 of human origin by WB, IP, IF and ELISA non cross-reactive with other REEP family members also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of REEP5 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of REEP5 of human origin |
| Entrez Gene | 7905 |
|---|
Application
Western blot analysis of REEP5 expression in non-transfected: (A) and human REEP5 transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of REEP5 expression in HeLa (A), HL-60 (B), Jurkat (C), K-562 (D), MCF7 (E) and HISM (F) whole cell lysates.| Application Notes | recommended for detection of REEP5 of human origin by WB, IP, IF and ELISA non cross-reactive with other REEP family members also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
