| Product Name | L-type Ca++CP γ3 Antibody (H-46) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 187-232 mapping within an internal region of L-type Ca++CP γ3 of human origin |
| Modification Notes | Voltage-dependent calcium channels are important for the release of neurotransmitters into neurons. L-type (long lasting current) voltage-dependent calcium channels are composed of four subunits: an å1 subunit, a ∫ subunit, a © subunit and an å2/∂ subunit. The © subunit is made of eight distinct proteins (designated L-type Ca++ CP ©1-©8) and functions by influencing the properties of the calcium current. L-type Ca++ CP ©3, also known as CACNG3 or Cacng2, is a 315 amino acid multi-pass membrane protein that belongs to the CACNG family. As one of the eight gamma subunits, L-type Ca++ CP ©3 is thought to stabilize the calcium current when the calcium channel is in a closed (inactivated) state. Defects in the gene encoding L-type Ca++ CP ©3 may be associated with familial infantile convulsive disorder with paroxysomal choreoathetosis, an autosomal dominant neurological disorder. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of L-type Ca++CP γ3 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 187-232 mapping within an internal region of L-type Ca++CP &gamma 3 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 187-232 mapping within an internal region of L-type Ca++CP γ3 of human origin |
| Application Notes | recommended for detection of L-type Ca++CP γ3 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
