| Product Name | Pancreasin Antibody (H-40) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 93-133 mapping within an internal region of Pancreasin of human origin |
| Modification Notes | Serine proteases are important in many biological processes such as receptor activation, complement activation, coagulation and tissue remodeling. Pancreasin, also known as marapsin (MPN), channel activating protease 2-like protein (CAPH2) or protease, serine 27, is an N-glycosylated, secreted pancreatic tryptic serine peptidase and proteinase. Pancreasin is responsible for cleaving peptides after an arginine residue and may play a role in regulating cell growth and migration. It can be inhibited by benzamidine and Leupeptin. Pancreasin is closely related to prostatin, tryptase-g, Testisin and tryptase-e. These proteins share approximately 40% amino acid identity with tryptase-a and tryptase-b. They contain Cysteine residues that may form a disulfide link bewteen the propeptide and catalytic chain, a tryptic propeptide cleavage site and a C-terminal membrane anchor. Tryptase-e and the human Pancreasin protein lack the characteristic C-terminal membrane anchor. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Pancreasin of human origin by WB, IP, IF and ELISA also reactive with additional species, including canine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 93-133 mapping within an internal region of Pancreasin of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 93-133 mapping within an internal region of Pancreasin of human origin |
| Entrez Gene | 83886 |
|---|
| Application Notes | recommended for detection of Pancreasin of human origin by WB, IP, IF and ELISA also reactive with additional species, including canine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
