Application
Western blot analysis of IFITM3 expression in non-transfected (A) and human IFITM3 transfected (B) 293 whole cell lysates.Application
Western blot analysis of IFITM3 expression in HeLa whole cell lysate.| Product Name | IFITM3 Antibody (A-24) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of IFITM3 of human origin by WB, IP and ELISA |
| Conjugation | Agarose |
| Modification | Acetylated |
| Modification Notes | IFITM3 (interferon induced transmembrane protein 3), also known as 1-8U or IP15, is a multi-pass membrane protein that belongs to the IFITM (interferon inducible transmembrane) family of proteins. IFITM proteins are induced by type I and type II interferons and contain multiple interferon (IFN)-stimulated response elements (ISREs) in their promoter regions. IFITM proteins play important roles in many cellular processes and their expression requires the presence of the chromatin remodeling SWI/SNF-like BAF complexes. Cellular processes involving IFITM proteins include cellular anti-proliferative activities and homotypic cell adhesion functions of interferons. In addition, IFITM genes are often upregulated in various cancer cells, suggesting a possible role in carcinogenesis. Localizing to the membrane, IFITM3 is a 133 amino acid protein that is induced by IFN-å and IFN-©. IFITM3 expression can be regulated by TEF-1, Brg-1 and Sp1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIPWB |
| WB:1:100~1:500 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of IFITM3 of human origin by WB IP and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of IFITM3 of human origin by WB, IP and ELISA |
| Entrez Gene | 10410 |
|---|
Application
Western blot analysis of IFITM3 expression in non-transfected (A) and human IFITM3 transfected (B) 293 whole cell lysates.
Application
Western blot analysis of IFITM3 expression in HeLa whole cell lysate.| Application Notes | WB:1:100~1:500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
