| Modification Notes |
The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. YANK2, also known as STK32B (serine/threonine kinase 32B) or STKG6, is a 414 amino acid protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase family. Using magnesium as a cofactor, YANK2 functions to catalyze the ATP-dependent phosphorylation of target proteins and may play a role in various signaling events throughout the cell. Multiple isoforms of YANK2 exist due to alternatively splicing events. |