Application
Western blot analysis of ISYNA1 expression in non-transfected 293T: (A), human ISYNA1 transfected 293T: (B) and A549 (C) whole cell lysates.Application
Western blot analysis of ISYNA1 expression in non-transfected 293T: (A), human ISYNA1 transfected 293T: (B) and A549 (C) whole cell lysates.Application
Western blot analysis of ISYNA1 expression in non-transfected 293T: (A), mouse ISYNA1 transfected 293T: (B) and A549 (C) whole cell lysates.| Product Name | ISYNA1 Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 259-558 mapping at the C-terminus of ISYNA1 of human origin |
| Modification Notes | Myo-inositol is an important constituent of membrane phospholipids and is a precursor for the phosphoinositide signaling pathway. ISYNA1 (inositol-3-phosphate synthase 1), also known as IPS, INO1 or INOS, is a 558 amino acid enzyme belonging to the myo-inositol-1-phosphate synthase family. Highly expressed in testis, ovary, heart, placenta and pancreas, with weak expression in blood leukocytes, thymus, skeletal muscle and colon, SYNA1 is the key enzyme myo-inositol biosynthesis, as it catalyzes the conversion of glucose 6-phosphate to 1-myo-inositol 1-phosphate in a NAD-dependent manner. ISYNA1 is the rate-limiting enzyme in the synthesis of all inositol-containing compounds. ISYNA1 may be upregulated by E2F-1, and is inhibited by valproate (VPA) and lithium, which are mood-stabilizing drugs. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ISYNA1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and bovine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 259-558 mapping at the C-terminus of ISYNA1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 259-558 mapping at the C-terminus of ISYNA1 of human origin |
Application
Western blot analysis of ISYNA1 expression in non-transfected 293T: (A), human ISYNA1 transfected 293T: (B) and A549 (C) whole cell lysates.
Application
Western blot analysis of ISYNA1 expression in non-transfected 293T: (A), human ISYNA1 transfected 293T: (B) and A549 (C) whole cell lysates.
Application
Western blot analysis of ISYNA1 expression in non-transfected 293T: (A), mouse ISYNA1 transfected 293T: (B) and A549 (C) whole cell lysates.| Application Notes | recommended for detection of ISYNA1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and bovine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
