Application
Western blot analysis of KIF21A expression in rat brain tissue extract.| Product Name | KIF21A Antibody (H-105) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1136-1240 mapping within an internal region of KIF21A of human origin |
| Modification Notes | The kinesin superfamily proteins (KIFs) are microtubule-dependent molecular motors that transport membranous organelles and protein complexes in a microtubule- and ATP-dependent manner. Cells use KIFs to tightly control the direction, destination, and speed of transportation of a variety of important functional molecules, including mRNA. KIF21A is a 1,674 amino acid protein that contains three characteristic kinesin domains: an N-terminal head motor domain, a coiled-coil stalk region and a C-terminal tail. KIF21A is expressed in all nervous system tissues. Missense mutations in in the KIF21A gene lead to congenital fibrosis of the extraocular muscles type 1 (CFEOM1). CFEOM1 refers to a group of congenital eye movement disorders characterized by nonprogressive ophthalmoplegia that affects all of the extraocular muscles. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of KIF21A isoforms 1-4 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1136-1240 mapping within an internal region of KIF21A of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1136-1240 mapping within an internal region of KIF21A of human origin |
Application
Western blot analysis of KIF21A expression in rat brain tissue extract.| Application Notes | recommended for detection of KIF21A isoforms 1-4 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
