epitope mapping within an internal region of TMEM111 of human origin
Modification Notes
TMEM111, also known as POB is a 261 amino acid multi-pass membrane protein that exists as multiple alternatively spliced isoforms which are encoded by a gene that maps to human chromosome 3. Chromosome 3 is made up of about 214 million bases encoding over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of TMEM111 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other TMEM family members also reactive with additional species, including equine, canine, bovine, porcine and avian:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of TMEM111 of human origin
Tissue Specificity
epitope mapping within an internal region of TMEM111 of human origin
Western blot analysis of TMEM111 expression in NIH/3T3 whole cell lysate.
Application Notes
recommended for detection of TMEM111 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other TMEM family members also reactive with additional species, including equine, canine, bovine, porcine and avian:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.