recommended for detection of Ethanolamine kinase of mouse, human and hamster origin by WB, IP and ELISA
Modification Notes
Ethanolamine kinase (ETNK1) is a 452 amino acid member of the choline/ethanolamine kinase family. Localized to the cytoplasm, Ethanolamine kinase catalyzes the first step in phosphatidylethanolamine (PtdEtn) biosynthesis via the CDP-Etn pathway. Ethanolamine kinase is specific for ethanolamine and exhibits negligible kinase activity on choline. Expressed in kidney, liver, placenta, heart, leukocyte, ovary and testis, Ethanolamine kinase exists as several isoforms as a result of alternative splicing events. The gene encoding Ethanolamine kinase maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and Trisomy 12p, which causes facial developmental defects and seizure disorders.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPELISA
WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
recommended for detection of Ethanolamine kinase of mouse human and hamster origin by WB IP and ELISA
Tissue Specificity
recommended for detection of Ethanolamine kinase of mouse, human and hamster origin by WB, IP and ELISA